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- Cullen Bryant
Years: 1974-1987
Games: 120
Rush Yards: 3119
Rush TD: 20
Y/A: 3.9
Y/G: 26.0
Picked up by the Rams in the 2nd Round of the 1973 NFL Draft out of Colorado, spent his first 4 years as the main return threat on special teams.
- Wendell Tyler
Years: 1977-1982
Games: 60
Rush Yards: 3266
Rush TD: 33
Y/A: 4.5
Y/G: 54.4
Selected in the 3rd round out of UCLA in the 1977 NFL Draft. In 1984, rushed for a 49er record 1262 yards. First player ever to lead 2 different teams in rush yards in 2 different superbowls.
- Tank Younger
Years: 1949-1957
Games: 100
Rush Yards: 3296
Rush TD: 31
Y/A: 4.8
Y/G: 33.0
Signed with the Rams as a free agent, as he was undrafted out of college. Became the first NFL player from a historically black college, playing under Grambling State legend Eddie Robinson. Was named to the pro bowl 4 times.

- Les Josephson
Years: 1964-1974
Games: 129
Rush Yards: 3407
Rush TD: 17
Y/A: 4.3
Y/G: 26.4
Minnesota native played in the 1967 pro bowl, after having his best professional season with 800 yards rushing. Played through many career-threatening injuries and retired in 1975 with the 3rd highest career rush yards total in Rams history.
- Dan Towler
Years: 1950-1955
Games: 67
Rush Yards: 3493
Rush TD: 43
Y/A: 5.2
Y/G: 52.1
The NFL’s leading rusher in 1952. Over a 3 year span, from 1951-1953, he had 2,627 rush yards, 6.05 Y/A to go along with 23 touchdowns. Considering that there were only 12 games in the regular season during this era, the aforementioned numbers indicate that he was nothing short of unstoppable.